Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9011753 | 0.98 | — | — | |
| SCHEMBL28947049 | 0.82 | — | — | |
| SCHEMBL7879 | 0.82 | — | — | |
| SCHEMBL531924 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL221474 | 0.80 | — | — | |
| Ethylenediamine SCHEMBL10527046 | 0.80 | — | — | |
| SCHEMBL1070324 | 0.80 | CYP1A2 (0.32) | CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL28375754 | 0.79 | CYP1A2 (0.34) | CYP1A2CYP2D6 | |
| Iodomethane SCHEMBL6702889 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL2237708 | 0.78 | CYP1A2 (0.31) | CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839798-B1 | Intermediates for preparating non-peptide retroviral protease inhibitors | ABBOTT LAB (US) | 2005-08-17 | — | — | EP | disclosed |
| EP-0839798-A2 | Intermediates for preparating non-peptide retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1998-05-06 | — | — | EP | disclosed |
| US-5670675-A | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1997-09-23 | — | — | US | disclosed |
| US-5545750-A | TREATING HUMAN IMMUNODEFICIENCY VIRUS | ABBOTT LABORATORIES (US) | 1996-08-13 | — | — | US | disclosed |
| US-5142056-A | Human immunodeficiency virus protease inhibitor | ABBOTT LABORATORIES (US) | 1992-08-25 | — | — | US | disclosed |
| EP-0402646-A1 | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1990-12-19 | — | — | EP | disclosed |