Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11233584 | 0.84 | TSHR (0.31) | TSHRTDP1 | |
| SCHEMBL9474443 | 0.81 | TSHR (0.40) | TSHRALDH1A1TDP1 | |
| SCHEMBL11237533 | 0.79 | TSHR (0.37) | TSHR | |
| SCHEMBL30094966 | 0.77 | TSHR (0.42) | TSHR | |
| SCHEMBL30620386 | 0.77 | TSHR (0.42) | TSHR | |
| SCHEMBL23579190 | 0.77 | TSHR (0.42) | TSHR | |
| SCHEMBL2430576 | 0.77 | TSHR (0.42) | TSHR | |
| SCHEMBL28899886 | 0.77 | TSHR (0.42) | TSHR | |
| SCHEMBL22110202 | 0.76 | TSHR (0.40) | TSHRALDH1A1TDP1 | |
| SCHEMBL1711205 | 0.76 | TSHR (0.33) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6858679-B2 | Compositions providing improved functionalization of terminal anions and processes for improved functionalization of terminal anions | FMC CORPORATION (US) | 2005-02-22 | — | — | US | disclosed |
| EP-1028982-B1 | COMPOSITIONS PROVIDING IMPROVED FUNCTIONALIZATION OF TERMINAL ANIONS AND PROCESSES FOR IMPROVED FUNCTIONALIZATION OF TERMINAL ANIONS | FMC CORP (US) | 2003-10-29 | — | — | EP | disclosed |
| US-20030153693-A1 | Compositions providing improved functionalization of terminal anions and processes for improved functionalization of terminal anions | QUIRK RODERIC PAUL (US) | 2003-08-14 | — | — | US | disclosed |
| US-6605564-B1 | Anionic polymerization initiators and salt additives selected from sodium chloride, sodium iodide, potassium chloride, potassium t-butoxide, for increasing the efficiency of reactions between living polymer anions and electrophiles | FMC CORPORATION | 2003-08-12 | — | — | US | disclosed |
| US-6545103-B2 | Living polymers | FMC CORPORATION | 2003-04-08 | — | — | US | disclosed |
| US-20020010082-A1 | Compositions providing improved functionalization of terminal anions and processes for improved functionalization of terminal anions | FMC CORPORATION | 2002-01-24 | — | — | US | disclosed |
| EP-1028982-A1 | COMPOSITIONS PROVIDING IMPROVED FUNCTIONALIZATION OF TERMINAL ANIONS AND PROCESSES FOR IMPROVED FUNCTIONALIZATION OF TERMINAL ANIONS | FMC CORPORATION (US) | 2000-08-23 | — | — | EP | disclosed |
| WO-1999025740-A1 | COMPOSITIONS PROVIDING IMPROVED FUNCTIONALIZATION OF TERMINAL ANIONS AND PROCESSES FOR IMPROVED FUNCTIONALIZATION OF TERMINAL ANIONS | FMC CORPORATION (US) | 1999-05-27 | — | — | WO | disclosed |
| US-5235065-A | PROCESS FOR THE PREPARATION OF A D-(+)-BIOTIN INTERMEDIATE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-08-10 | — | — | US | disclosed |