Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.41 |
| ▸ | PARP1 | P09874 | 3/20 | 0.41 |
| ▸ | AURKA | O14965 | 2/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.41 |
| ▸ | RET | P07949 | 2/20 | 0.41 |
| ▸ | IGF1R | P08069 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | CLK2 | P49760 | 2/20 | 0.41 |
| ▸ | GSK3A | P49840 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | PRKX | P51817 | 2/20 | 0.41 |
| ▸ | BTK | Q06187 | 2/20 | 0.41 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.41 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.41 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13184288 | 0.84 | CSNK2A1 (0.41) | CSNK2A1DYRK1APARP1AURKADAPK3 | |
| SCHEMBL197041 | 0.83 | CSNK2A1 (0.47) | CSNK2A1DYRK1APARP1AURKADAPK3 | |
| SCHEMBL4560164 | 0.83 | PARP1 (0.46) | CSNK2A1DYRK1APARP1ABL1HSD17B10 | |
| SCHEMBL6876629 | 0.78 | PARP1 (0.42) | CSNK2A1DYRK1APARP1ABL1LRRK2 | |
| SCHEMBL4612059 | 0.76 | SLC6A2 (0.43) | CSNK2A1DYRK1APARP1RAB9AHTT | |
| SCHEMBL6950307 | 0.76 | PARP1 (0.41) | CSNK2A1DYRK1APARP1ABL1HSD17B10 | |
| SCHEMBL20200208 | 0.72 | CSNK2A1 (0.41) | CSNK2A1DYRK1APARP1AURKADAPK3 | |
| SCHEMBL1355302 | 0.71 | PDPK1 (0.38) | PARP1HSD17B10PDPK1ALDH1A1CYP1A2 | |
| SCHEMBL18225451 | 0.71 | KDM5A (0.59) | CSNK2A1DYRK1APARP1AURKADAPK3 | |
| SCHEMBL18948981 | 0.71 | BRD4 (0.46) | PARP1LRRK2HSD17B10HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012065062-A1 | NOVEL ANTIVIRAL COMPOUNDS | PHARMARESOURCES(SHANGHAI)CO., LTD. (CN) | 2012-05-18 | — | — | WO | disclosed |