SCHEMBL6448078

SCHEMBL6448078

CCCC(=O)N1CC[C@@H](NS(=O)(=O)c2ccc(NC(=O)c3ccccc3C)c3ccccc23)C(C)C1

nearest known ligand 0.80

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CCR8 P51685 20/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1337174 1.00 CCR8 (0.80) CCR8
SCHEMBL13933726 1.00 CCR8 (0.80) CCR8
SCHEMBL1338562 1.00 CCR8 (0.80) CCR8
SCHEMBL1337172 1.00 CCR8 (0.80) CCR8
SCHEMBL1339735 1.00 CCR8 (0.80) CCR8
SCHEMBL1339726 1.00 CCR8 (0.80) CCR8
SCHEMBL6228054 1.00 CCR8 (0.80) CCR8
SCHEMBL12129492 1.00 CCR8 (0.80) CCR8
SCHEMBL1339386 0.92 CCR8 (0.80) CCR8
SCHEMBL1339320 0.92 CCR8 (0.80) CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1581511-A1 CCR8 INHIBITORS MILLENNIUM PHARMACEUTICALS, INC. (US) 2005-10-05 EP disclosed
WO-2004058736-A1 CCR8 INHIBITORS MILLENNIUM PHARMACEUTICALS, INC. (US) 2004-07-15 WO disclosed