Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | IP6K1 | Q92551 | 5/20 | 0.38 |
| ▸ | IP6K3 | Q96PC2 | 5/20 | 0.38 |
| ▸ | IP6K2 | Q9UHH9 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12870488 | 0.88 | HDAC1 (0.42) | CYP1A2CYP2C8HDAC1IP6K1IP6K3 | |
| SCHEMBL12870947 | 0.79 | HDAC1 (0.46) | HDAC1IP6K1IP6K3IP6K2ALDH1A1 | |
| SCHEMBL12870909 | 0.78 | IP6K1 (0.41) | CYP1A2CYP2C8HDAC1IP6K1IP6K3 | |
| SCHEMBL6368019 | 0.77 | HDAC1 (0.41) | CYP1A2CYP2C8HDAC1IP6K1IP6K3 | |
| SCHEMBL13680381 | 0.77 | CYP1A2 (0.59) | CYP1A2CYP2C8CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL15109258 | 0.76 | CYP1A2 (0.62) | CYP1A2CYP2C8CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL14532895 | 0.76 | HDAC1 (0.41) | CYP1A2CYP2C8HDAC1IP6K1IP6K3 | |
| SCHEMBL15109235 | 0.75 | CYP3A4 (0.70) | CYP1A2CYP2C8CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL13680392 | 0.74 | CYP3A4 (0.69) | CYP1A2CYP2C8CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL973374 | 0.74 | AKT1 (0.47) | CYP1A2CYP2C8HDAC1IP6K1IP6K3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130261134-A1 | MESYLATE SALT FORMS OF A POTENT HCV INHIBITOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-10-03 | — | — | US | disclosed |
| US-20120122887-A1 | SOLID STATE FORMS OF A POTENT HCV INHIBITOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122887-A1 | SOLID STATE FORMS OF A POTENT HCV INHIBITOR | HAVCR2, SLC10A1, ZC3HAV1 | CYP1A2 2833/4885CYP2C8 1783/4885HDAC1 289/4885 |
| US-20130261134-A1 | MESYLATE SALT FORMS OF A POTENT HCV INHIBITOR | SLC10A1, HAVCR2, ABL1 | CYP1A2 2228/4885CYP2C8 1086/4885HDAC1 813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.