Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 17/20 | 0.60 |
| ▸ | ESR1 | P03372 | 16/20 | 0.60 |
| ▸ | KDM6B | O15054 | 1/20 | 0.52 |
| ▸ | KDM6A | O15550 | 1/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.45 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9272942 | 0.83 | KDM4E (0.58) | HSPD1PTPN2PTPN1PTPN5HSPE1 | |
| SCHEMBL19428496 | 0.83 | PIK3CB (0.57) | ESR2ESR1KDM6BKDM6APIK3CA | |
| SCHEMBL28267506 | 0.82 | PSMB8 (0.54) | KDM6BKDM6AHSPD1PTPN2PTPN1 | |
| SCHEMBL9269982 | 0.80 | MAPT (0.44) | ESR2ESR1HSPD1PTPN2PTPN1 | |
| SCHEMBL9115528 | 0.78 | ESR1 (0.65) | ESR2ESR1KDM6BKDM6APIK3CA | |
| SCHEMBL16744046 | 0.76 | TOP2A (0.51) | ESR2ESR1KDM6BKDM6A | |
| SCHEMBL29730425 | 0.76 | GSK3B (0.44) | ESR2ESR1HSPD1PTPN2PTPN1 | |
| SCHEMBL19434362 | 0.76 | GSK3B (0.44) | ESR2ESR1HSPD1PTPN2PTPN1 | |
| SCHEMBL1378665 | 0.76 | ESR1 (1.00) | ESR2ESR1KDM6BKDM6APIK3CA | |
| SCHEMBL1375754 | 0.75 | ESR1 (1.00) | ESR2ESR1KDM6BKDM6APIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050244718-A1 | Polymerizable, luminescent compounds and mixtures, luminescent polymer materials and their use | MERCK PATENT GMBH (DE) | 2005-11-03 | — | — | US | disclosed |
| EP-1517974-A1 | POLYMERIZABLE, LUMINESCENT COMPOUNDS AND MIXTURES, LUMINESCENT POLYMER MATERIALS AND THEIR USE | MERCK PATENT GmbH (DE) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004003103-A1 | POLYMERIZABLE, LUMINESCENT COMPOUNDS AND MIXTURES, LUMINESCENT POLYMER MATERIALS AND THEIR USE | MERCK PATENT GMBH (DE) | 2004-01-08 | — | — | WO | disclosed |