SCHEMBL6448955

SCHEMBL6448955

CC1=C(C)C(C)C([Si](C)(C)NC=O)=C1C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6439365 0.98
SCHEMBL6438616 0.75
SCHEMBL8220098 0.74
SCHEMBL7054648 0.69
SCHEMBL3688468 0.69
SCHEMBL15417819 0.69
SCHEMBL14153012 0.69
SCHEMBL5677185 0.69
SCHEMBL7935893 0.69
SCHEMBL5616372 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6858557-B1 Supported constrained geometry olefin polymerization catalysts THE DOW CHEMICAL COMPANY (US) 2005-02-22 US disclosed
US-6806326-B2 TITANIUM COMPLEXES WITH DELOCALIZED PI-BONDED CYCLOPENTADIENYL MOIETY, AND COCATALYST; FOR EXAMPLE, 1-(TERT-BUTYLAMIDO)-2-(TETRAMETHYLCYCLOPENTADIENYL)-ETHANEDIYL TITANIUM DICHLORIDE AND METHYL ALUMOXANE THE DOW CHEMICAL COMPANY 2004-10-19 US disclosed
US-6686488-B2 USING COORDINATION POLYMERIZATION CATALYSTS THE DOW CHEMICAL COMPANY 2004-02-03 US disclosed
US-20030065203-A1 Constrained geometry addition polymerization catalysts WILSON DAVID R (US) 2003-04-03 US disclosed
US-20020128403-A1 Constrained geometry addition polymerization catalysts STEVENS JAMES C (US) 2002-09-12 US disclosed
US-6075077-A ETHYLENE COPOLYMER PREPARED USING A CYCLOPENTADIENE COORDINATION COMPLEX OF GIVEN FORMULA WHERE METAL IS BOUND TO A DELOCALIZED SUBSTITUTED PI-BONDED MOIETY TO INDUCE A CONSTRAINED GEOMETRY ABOUT THE METAL, AND COCATALYST THE DOW CHEMICAL COMPANY (US) 2000-06-13 US disclosed
US-5703187-A ETHYLENICALLY UNSATURATED ADDITION POLYMERS THE DOW CHEMICAL COMPANY (US) 1997-12-30 US disclosed
EP-0416815-B1 Constrained geometry addition polymerization catalysts, processes for their preparation, precursors therefor, methods of use, and novel polymers formed therewith DOW CHEMICAL CO (US) 1997-08-13 EP disclosed