Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | F3 | P13726 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2127064 | 0.92 | CA12 (0.44) | EP300CA12CA1CA9MMP1 | |
| SCHEMBL8604922 | 0.92 | EP300 (0.46) | EP300CA12CA1CA9MMP1 | |
| SCHEMBL6157470 | 0.86 | CA12 (0.45) | EP300CA12CA1CA9MMP1 | |
| SCHEMBL1023434 | 0.86 | EP300 (0.47) | EP300CA12CA1CA9MMP2 | |
| SCHEMBL8415797 | 0.85 | EP300 (0.47) | EP300CA12CA1CA9MMP2 | |
| SCHEMBL5691846 | 0.85 | EP300 (0.47) | EP300CA12CA1CA9MMP2 | |
| SCHEMBL4977299 | 0.83 | CA12 (0.42) | EP300CA12CA1CA9MMP1 | |
| SCHEMBL906434 | 0.80 | EP300 (0.48) | EP300MMP2GRIK1F7F3 | |
| SCHEMBL8604924 | 0.80 | CA12 (0.40) | EP300CA12CA1CA9GRIK1 | |
| SCHEMBL8849789 | 0.79 | EP300 (0.58) | EP300MMP2F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509568-A1 | RUBBER MIXTURES CONTAINING QUATERNARY POLYMERS AND POLAR SOFTENING AGENTS | Lanxess Deutschland GmbH (DE) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003099921-A1 | RUBBER MIXTURES CONTAINING QUATERNARY POLYMERS AND POLAR SOFTENING AGENTS | LANXESS DEUTSCHLAND GMBH (DE) | 2003-12-04 | — | — | WO | disclosed |
| US-20020120086-A1 | Quaternary polymers with functional amine groups field of the invention | BAYER AKTIENGESELLSCHAFT (DE) | 2002-08-29 | — | — | US | disclosed |