Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4173932 | 0.91 | MAPT (0.35) | MAPTNPY5RALDH1A1GLAROCK2 | |
| SCHEMBL4158592 | 0.78 | CYP2C9 (0.38) | CYP1A2CYP2C9MAPTPOLBNPY5R | |
| SCHEMBL4173946 | 0.74 | MAPT (0.35) | MAPTNPY5RMEN1KMT2AALDH1A1 | |
| SCHEMBL4173277 | 0.72 | HPGD (0.31) | HSD17B10HPGDTSHR | |
| SCHEMBL4160554 | 0.72 | PARP1 (0.36) | CYP2C9MAPTPOLBNPY5RMEN1 | |
| SCHEMBL4175164 | 0.71 | RECQL (0.39) | MAPTPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL4170513 | 0.71 | SMN1; SMN2 (0.35) | MAPTPOLBNPY5RALDH1A1GLA | |
| Leteprinim SCHEMBL358492 | 0.70 | HSD17B10 (0.42) | CYP1A2CYP2C9MAPTPOLBMEN1 | |
| SCHEMBL4158588 | 0.69 | MAPT (0.37) | MAPTMEN1KMT2AALDH1A1GLA | |
| SCHEMBL4836350 | 0.68 | CYP2C9 (0.46) | CYP1A2CYP2C9MAPTPOLBNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1525205-A2 | NOVEL SUBSTITUTED PYRAZOLO( 1,5-A /I ]-1,3,5-TRIAZINE DERIVATIVES AND THEIR ANALOGUES, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, USE THEREOF AS MEDICINE AND METHODS FOR PREPARING SAME | Greenpharma (FR) | 2005-04-27 | — | — | EP | disclosed |
| WO-2004011464-A2 | NOVEL SUBSTITUTED PYRAZOLO[1,5 A]-1,3,5-TRIAZINE DERIVATIVES AND THEIR ANALOGUES, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, USE THEREOF AS MEDICINE AND METHODS FOR PREPARING SAME | GREENPHARMA (FR) | 2004-02-05 | — | — | WO | disclosed |