Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB2 | Q9UBS0 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6449709 | 1.00 | RPS6KB2 (0.41) | RPS6KB2HSD17B10MAPK1TSHRKDM4E | |
| SCHEMBL6449710 | 1.00 | RPS6KB2 (0.41) | RPS6KB2HSD17B10MAPK1TSHRKDM4E | |
| SCHEMBL6450450 | 0.82 | PDE4D (0.38) | HSD17B10MAPK1TSHRKDM4EALDH1A1 | |
| SCHEMBL6450454 | 0.82 | PDE4D (0.38) | HSD17B10MAPK1TSHRKDM4EALDH1A1 | |
| SCHEMBL6450452 | 0.82 | PDE4D (0.38) | HSD17B10MAPK1TSHRKDM4EALDH1A1 | |
| SCHEMBL6442363 | 0.80 | S1PR1 (0.39) | KDM4EALDH1A1GAAPDE4DMAPT | |
| SCHEMBL6442355 | 0.80 | S1PR1 (0.39) | KDM4EALDH1A1GAAPDE4DMAPT | |
| SCHEMBL6442359 | 0.80 | S1PR1 (0.39) | KDM4EALDH1A1GAAPDE4DMAPT | |
| SCHEMBL6453982 | 0.79 | PDE4D (0.40) | MAPK1PDGFRBPDGFRAPDE4DHTT | |
| SCHEMBL6453976 | 0.79 | PDE4D (0.40) | MAPK1PDGFRBPDGFRAPDE4DHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884802-B2 | 6-heteroarylphenanthridines | ALTANA PHARMA AG (DE) | 2005-04-26 | — | — | US | disclosed |
| US-20040038979-A1 | Treating airway disorders such as asthma. | ALTANA PHARMA AG (DE) | 2004-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040038979-A1 | Treating airway disorders such as asthma. | PTGER4, PDE4B, PDE4A | RPS6KB2 1837/4885HSD17B10 1564/4885MAPK1 3164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.