SCHEMBL6449772

SCHEMBL6449772

[CH2]C(=COC(=O)CC(C)=O)OC(=O)CC(C)=O

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.43
GAA P10253 1/20 0.43
SI P14410 1/20 0.43
MGAM2 Q2M2H8 1/20 0.43
KDM4E B2RXH2 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6449776 0.79 MGAM (0.46) MGAMGAASIMGAM2
SCHEMBL27281470 0.76 MGAM (0.52) MGAMGAASIMGAM2KDM4E
SCHEMBL27815742 0.73 MGAM (0.44) MGAMGAASIMGAM2
SCHEMBL562094 0.73 MGAM (0.44) MGAMGAASIMGAM2
SCHEMBL29163762 0.73 MGAM (0.55) MGAMGAASIMGAM2KDM4E
SCHEMBL465128 0.73
SCHEMBL27403155 0.72 MGAM (0.48) MGAMGAASIMGAM2
SCHEMBL28073484 0.72 MGAM (0.48) MGAMGAASIMGAM2
SCHEMBL449524 0.72 MGAM (0.67) MGAMGAASIMGAM2KDM4E
SCHEMBL9287460 0.72 MGAM (0.52) MGAMGAASIMGAM2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050101723-A1 For bonding laminates; a (meth)acrylic acid and a carboxyl-reactive monomer with a molecular weight less than 800 ZHAO CHEN Q (US) 2005-05-12 US disclosed
EP-1420054-A1 Curable adhesive compositions ROHM AND HAAS COMPANY (US) 2004-05-19 EP disclosed