Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.49 |
| ▸ | F2 | P00734 | 11/20 | 0.44 |
| ▸ | F7 | P08709 | 5/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.42 |
| ▸ | MASP2 | O00187 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.40 |
| ▸ | F9 | P00740 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6450171 | 1.00 | F10 (0.49) | F10F2F7PRSS1KLKB1 | |
| Hydrochloric Acid SCHEMBL5045149 | 0.99 | F10 (0.50) | F10F2F7PRSS1KLKB1 | |
| Hydrochloric Acid SCHEMBL5045141 | 0.99 | F10 (0.50) | F10F2F7PRSS1KLKB1 | |
| SCHEMBL6448894 | 0.92 | F10 (0.57) | F10F2F7PRSS1KLKB1 | |
| SCHEMBL6448900 | 0.92 | F10 (0.57) | F10F2F7PRSS1KLKB1 | |
| SCHEMBL5038128 | 0.92 | F10 (0.51) | F10F2F7PRSS1KLKB1 | |
| Hydrochloric Acid SCHEMBL5045416 | 0.91 | F10 (0.48) | F10F2F7PRSS1KLKB1 | |
| Hydrochloric Acid SCHEMBL5045435 | 0.91 | F10 (0.48) | F10F2F7PRSS1KLKB1 | |
| Hydrochloric Acid SCHEMBL5038105 | 0.90 | F10 (0.49) | F10F2F7PRSS1KLKB1 | |
| Hydrochloric Acid SCHEMBL5038113 | 0.90 | F10 (0.49) | F10F2F7PRSS1KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567498-A2 | MANDELIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004048335-A2 | MANDELIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-06-10 | — | — | WO | disclosed |