SCHEMBL645025

SCHEMBL645025

Nc1[c]c(N)ccc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1027850 0.78
SCHEMBL2321538 0.78
SCHEMBL5705211 0.78
SCHEMBL21586 0.78
SCHEMBL10884854 0.73
SCHEMBL6841722 0.73 CHEK1 (0.34)
SCHEMBL6221220 0.73 TSHR (0.37)
SCHEMBL22106 0.62
SCHEMBL15641755 0.61
SCHEMBL292329 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344695-A Hydroxyl-enriched cycloolefin copolymer long afterglow material and application thereof 重庆理工大学 2024-07-16 CN claimed
CN-105853246-B Keratin dyeing compositions and application thereof comprising free radical scavenger and chelating agent 诺赛尔股份有限公司 2019-07-26 CN claimed
US-8975259-B2 Compositions and methods for inhibiting G protein signaling UNIVERSITY OF ROCHESTER (US) 2015-03-10 US claimed
US-20100130505-A1 COMPOSITIONS AND METHODS FOR INHIBITING G PROTEIN SIGNALING UNIVERSITY OF ROCHESTER (US) 2010-05-27 US claimed
EP-2147310-A2 COMPOSITIONS AND METHODS FOR INHIBITING G PROTEIN SIGNALING University of Rochester (US) 2010-01-27 EP claimed
WO-2009020677-A9 COMPOSITIONS AND METHODS FOR INHIBITING G PROTEIN SIGNALING UNIV ROCHESTER (US) 2009-04-16 WO claimed
WO-2009020677-A2 COMPOSITIONS AND METHODS FOR INHIBITING G PROTEIN SIGNALING UNIVERSITY OF ROCHESTER (US) 2009-02-12 WO claimed
US-20080139588-A1 Pyrrolo[2,3-d]pyrimidine cytokine inhibitors THE PROCTER & GAMBLE COMPANY 2008-06-12 US claimed
CN-118344695-A Hydroxyl-enriched cycloolefin copolymer long afterglow material and application thereof 重庆理工大学 2024-07-16 CN disclosed
CN-110650944-B Silica-based zinc catalysts, their preparation and use in the alkoxycarbonylation of amines 科思创德国股份有限公司 2022-07-19 CN disclosed
WO-2021132326-A1 TETRAAZAPORPHYRIN COMPOUND, INK COMPOSITION, FILM, OPTICAL MATERIAL, OPTICAL FILM, DISPLAY SURFACE FILM, AND DISPLAY DEVICE 大日本印刷株式会社 2021-07-01 WO disclosed
EP-3425431-A2 LAMINATED FILM, AND DISPLAY DEVICE INCLUDING SAME Samsung Electronics Co., Ltd. (KR) 2019-01-09 EP disclosed
CN-104861990-B Aligning agent for liquid crystal, liquid crystal orientation film and liquid crystal display element JSR株式会社 2018-06-08 CN disclosed
CN-104178181-B Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display element 奇美实业股份有限公司 2017-04-12 CN disclosed
EP-0513387-A1 ACTIVE OXYGEN INHIBITOR OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1992-11-19 EP disclosed
EP-0498680-A1 New beta-amino-alpha-hydroxycarboxylic acids and their use Sankyo Company Limited (JP) 1992-08-12 EP disclosed
EP-0437016-A2 Lipid A analogues having immunoactivating and anti-tumour activity Sankyo Company Limited (JP) 1991-07-17 EP disclosed
CN-1052481-A Lipoid category-A with immunocompetence and anti-tumor activity is like thing SANKYO CO (JP) 1991-06-26 CN disclosed
EP-0382185-A2 Carbostyril derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1990-08-16 EP disclosed
EP-0138766-A2 Process for the preparation of substituted 1-phenyl indanes CIBA-GEIGY AG (CH) 1985-04-24 EP disclosed