Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 9/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 5/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.36 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.36 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11752118 | 1.00 | KDM4E (0.45) | KDM4ETSHRGRIK1GRIK2GRIA2 | |
| SCHEMBL11746179 | 0.84 | TSHR (0.42) | KDM4ETSHRGRIK1GRIK2GRIA2 | |
| SCHEMBL11748378 | 0.82 | KDM4E (0.43) | KDM4ETSHRGRIK1GRIK2GRIA2 | |
| SCHEMBL3627154 | 0.80 | KDM4E (0.50) | KDM4ETSHRGRIK1GRIK2GRIA2 | |
| SCHEMBL7700265 | 0.80 | KDM4E (0.50) | KDM4ETSHRGRIK1GRIK2GRIA2 | |
| SCHEMBL3627155 | 0.80 | KDM4E (0.50) | KDM4ETSHRGRIK1GRIK2GRIA2 | |
| SCHEMBL11747407 | 0.80 | KDM4E (0.42) | KDM4ETSHRGRIK1GRIK2GRIA2 | |
| SCHEMBL10937515 | 0.78 | KDM4E (0.48) | KDM4ETSHRGRIK1GRIK2GRIA2 | |
| SCHEMBL10937503 | 0.78 | KDM4E (0.48) | KDM4ETSHRGRIK1GRIK2GRIA2 | |
| SCHEMBL8778828 | 0.78 | KDM4E (0.48) | KDM4ETSHRGRIK1GRIK2GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1565509-A1 | CATALYTIC COMPOSITION OF ORGANOTIN COMPOUNDS | Crompton GmbH (DE) | 2005-08-24 | — | — | EP | disclosed |
| WO-2004050742-A1 | CATALYTIC COMPOSITION OF ORGANOTIN COMPOUNDS | CROMPTON GMBH (DE) | 2004-06-17 | — | — | WO | disclosed |