Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 15/20 | 0.66 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.66 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6450426 | 0.99 | F2 (0.66) | F2PRSS1F10 | |
| SCHEMBL6470407 | 0.84 | F2 (0.77) | F2PRSS1F10 | |
| Hydrochloric Acid SCHEMBL6450704 | 0.83 | F2 (0.76) | F2PRSS1F10 | |
| Hydrochloric Acid SCHEMBL7708448 | 0.80 | F2 (0.68) | F2PRSS1 | |
| Hydrochloric Acid SCHEMBL6455796 | 0.80 | F2 (0.86) | F2PRSS1 | |
| Hydrochloric Acid SCHEMBL6452736 | 0.79 | F2 (0.99) | F2PRSS1F10 | |
| Hydrochloric Acid SCHEMBL6454532 | 0.79 | F2 (0.87) | F2PRSS1F10 | |
| Hydrochloric Acid SCHEMBL6454490 | 0.78 | F2 (0.99) | F2PRSS1F10 | |
| Hydrochloric Acid SCHEMBL6453121 | 0.78 | F2 (0.99) | F2PRSS1F10 | |
| Hydrochloric Acid SCHEMBL6450472 | 0.77 | F2 (0.99) | F2PRSS1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1505062-A1 | Heterocyclic derivatives and their use as antithrombotic agents | Akzo Nobel N.V. (NL) | 2005-02-09 | — | — | EP | disclosed |
| US-6444672-B1 | ORAL BIOVAILABILITY; INHIBITORS OF THROMBIN AND/OR FACTOR XA; SERINE PROTEASE INHIBITOR | AKZO NOBEL N.V. (NL) | 2002-09-03 | — | — | US | disclosed |
| US-6432955-B1 | ANTICOAGULANTS | AKZO NOBEL N.V. (NL) | 2002-08-13 | — | — | US | disclosed |