Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FPR1 | P21462 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6450994 | 1.00 | KDM1A (0.44) | KDM1ASLC6A2SLC6A4SLC6A3PDE4B | |
| SCHEMBL6464221 | 0.90 | KDM1A (0.43) | KDM1ASLC6A2SLC6A4SLC6A3PDE4B | |
| SCHEMBL6464226 | 0.90 | KDM1A (0.43) | KDM1ASLC6A2SLC6A4SLC6A3PDE4B | |
| SCHEMBL6459981 | 0.89 | KDM1A (0.42) | KDM1ASLC6A2SLC6A4SLC6A3PDE4B | |
| SCHEMBL6459984 | 0.89 | KDM1A (0.42) | KDM1ASLC6A2SLC6A4SLC6A3PDE4B | |
| SCHEMBL6459978 | 0.89 | KDM1A (0.42) | KDM1ASLC6A2SLC6A4SLC6A3PDE4B | |
| SCHEMBL6452288 | 0.88 | EPHX2 (0.36) | KDM1A | |
| SCHEMBL6454243 | 0.88 | PDE4B (0.34) | KDM1ASLC6A2SLC6A4SLC6A3PDE4B | |
| SCHEMBL6454239 | 0.88 | PDE4B (0.34) | KDM1ASLC6A2SLC6A4SLC6A3PDE4B | |
| SCHEMBL6452293 | 0.88 | EPHX2 (0.36) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |