Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAN2A1 | Q16706 | 2/20 | 0.37 |
| ▸ | MAN1B1 | Q9UKM7 | 2/20 | 0.37 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20595715 | 0.83 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20595781 | 0.83 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20595789 | 0.79 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20595778 | 0.79 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20142303 | 0.78 | GBA1 (0.46) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20142304 | 0.78 | GBA1 (0.46) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7007764 | 0.78 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL6336901 | 0.76 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL6541046 | 0.76 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL6540298 | 0.76 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1492794-A1 | PIPERAZINE SUBSTITUTED ARYL BENZODIAZEPINES AND THEIR USE AS DOPAMINE RECEPTOR ANTAGONISTS FOR THE TREATMENT OF PSYCHOTIC DISORDERS | ELI LILLY AND COMPANY (US) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003082877-A1 | PIPERAZINE SUBSTITUTED ARYL BENZODIAZEPINES AND THEIR USE AS DOPAMINE RECEPTOR ANTAGONISTS FOR THE TREATMENT OF PSYCHOTIC DISORDERS | ELI LILLY AND COMPANY (US) | 2003-10-09 | — | — | WO | disclosed |