Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 6/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6451377 | 1.00 | OPRL1 (0.35) | OPRL1SLC6A3FPR2PROKR1CYP2C9 | |
| SCHEMBL6458258 | 0.94 | TP53 (0.34) | OPRL1 | |
| SCHEMBL6458262 | 0.94 | TP53 (0.34) | OPRL1 | |
| SCHEMBL6451660 | 0.93 | OPRL1 (0.33) | OPRL1 | |
| SCHEMBL6451662 | 0.93 | OPRL1 (0.33) | OPRL1 | |
| SCHEMBL6459238 | 0.92 | OPRL1 (0.33) | OPRL1 | |
| SCHEMBL6459342 | 0.92 | OPRL1 (0.33) | OPRL1 | |
| SCHEMBL6459244 | 0.92 | OPRL1 (0.33) | OPRL1 | |
| SCHEMBL6459345 | 0.92 | OPRL1 (0.33) | OPRL1 | |
| SCHEMBL6454374 | 0.91 | OPRL1 (0.34) | OPRL1SLC6A3FPR2PROKR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |