Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA1 | P02708 | 3/20 | 0.31 |
| ▸ | CHRNB1 | P11230 | 3/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.31 |
| ▸ | CHRNG | P07510 | 2/20 | 0.31 |
| ▸ | CHRND | Q07001 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6451585 | 1.00 | CHRNA1 (0.31) | CHRNA1CHRNB1CHRNB2SLC6A2CHRNB4 | |
| SCHEMBL6457272 | 0.86 | OPRL1 (0.31) | — | |
| SCHEMBL6457267 | 0.86 | OPRL1 (0.31) | — | |
| SCHEMBL6460869 | 0.85 | ESR2 (0.33) | — | |
| SCHEMBL6460866 | 0.85 | ESR2 (0.33) | — | |
| SCHEMBL6451848 | 0.84 | OPRL1 (0.32) | — | |
| SCHEMBL6451851 | 0.84 | OPRL1 (0.32) | — | |
| SCHEMBL6460334 | 0.83 | TP53 (0.32) | — | |
| SCHEMBL6460343 | 0.83 | TP53 (0.32) | — | |
| SCHEMBL6452006 | 0.82 | OPRL1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |