Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 5/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6451743 | 1.00 | HTR2C (0.44) | HTR2CSIGMAR1P2RY14KIF11ESR2 | |
| SCHEMBL6454212 | 0.87 | HTR2C (0.41) | HTR2CSIGMAR1P2RY14ESR2MEN1 | |
| SCHEMBL6454207 | 0.87 | HTR2C (0.41) | HTR2CSIGMAR1P2RY14ESR2MEN1 | |
| SCHEMBL17147613 | 0.86 | HTR2C (0.53) | HTR2CSIGMAR1P2RY14ESR2KDM1A | |
| SCHEMBL19102561 | 0.86 | HTR2C (0.53) | HTR2CSIGMAR1P2RY14ESR2KDM1A | |
| SCHEMBL17147616 | 0.86 | HTR2C (0.53) | HTR2CSIGMAR1P2RY14ESR2KDM1A | |
| SCHEMBL6455885 | 0.85 | APP (0.41) | HTR2CSIGMAR1P2RY14KIF11 | |
| SCHEMBL6455881 | 0.85 | APP (0.41) | HTR2CSIGMAR1P2RY14KIF11 | |
| SCHEMBL11280521 | 0.84 | HTR2C (0.56) | HTR2CSIGMAR1P2RY14KIF11ESR2 | |
| SCHEMBL26480380 | 0.84 | HTR2C (0.56) | HTR2CSIGMAR1P2RY14KIF11ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |