Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 5/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.43 |
| ▸ | F7 | P08709 | 3/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | PROC | P04070 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.39 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6451726 | 1.00 | F10 (0.50) | F10MAPK1F2PRSS1F7 | |
| Hydrochloric Acid SCHEMBL5045557 | 0.99 | F10 (0.51) | F10MAPK1F2PRSS1F7 | |
| Hydrochloric Acid SCHEMBL5045566 | 0.99 | F10 (0.51) | F10MAPK1F2PRSS1F7 | |
| SCHEMBL5041955 | 0.92 | F10 (0.48) | F10MAPK1F2PRSS1F7 | |
| SCHEMBL5041966 | 0.92 | F10 (0.48) | F10MAPK1F2PRSS1F7 | |
| Hydrochloric Acid SCHEMBL5041535 | 0.89 | F10 (0.49) | F10F2PRSS1F7KLKB1 | |
| Hydrochloric Acid SCHEMBL5041541 | 0.89 | F10 (0.49) | F10F2PRSS1F7KLKB1 | |
| Hydrochloric Acid SCHEMBL5041941 | 0.88 | F10 (0.53) | F10MAPK1F2PRSS1F7 | |
| Hydrochloric Acid SCHEMBL5041921 | 0.88 | F10 (0.53) | F10MAPK1F2PRSS1F7 | |
| Hydrochloric Acid SCHEMBL5037782 | 0.86 | F10 (0.54) | F10F2PRSS1F7CARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567498-A2 | MANDELIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004048335-A2 | MANDELIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-06-10 | — | — | WO | disclosed |