Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.81 |
| ▸ | PPARA | Q07869 | 14/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5913969 | 0.94 | PPARG (0.89) | PPARGPPARASIGMAR1NPC1RAB9A | |
| SCHEMBL6450149 | 0.92 | PPARG (0.85) | PPARGPPARASIGMAR1NPC1RAB9A | |
| SCHEMBL5913369 | 0.91 | PPARG (0.95) | PPARGPPARASIGMAR1NPC1RAB9A | |
| SCHEMBL5913603 | 0.90 | PPARG (1.00) | PPARGPPARASIGMAR1NPC1RAB9A | |
| SCHEMBL29496192 | 0.90 | PPARG (1.00) | PPARGPPARASIGMAR1NPC1RAB9A | |
| SCHEMBL7021537 | 0.90 | PPARG (0.81) | PPARGPPARASIGMAR1NPC1RAB9A | |
| SCHEMBL6477885 | 0.88 | PPARG (0.78) | PPARGPPARASIGMAR1NPC1RAB9A | |
| SCHEMBL5727831 | 0.87 | PPARG (0.76) | PPARGPPARASIGMAR1NPC1RAB9A | |
| SCHEMBL6485289 | 0.87 | PPARG (0.79) | PPARGPPARASIGMAR1NPC1RAB9A | |
| SCHEMBL5913680 | 0.87 | PPARG (0.79) | PPARGPPARASIGMAR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252150-B1 | HETEROCYCLIC DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2003-06-04 | — | — | EP | claimed |
| EP-1252150-A1 | NOVEL HETEROCYCLIC DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Les Laboratoires Servier (FR) | 2002-10-30 | — | — | EP | claimed |
| WO-2001057002-A1 | NOVEL HETEROCYCLIC DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2001-08-09 | — | — | WO | claimed |
| EP-1560598-A1 | ASSOCIATION BETWEEN A HETEROCYCLIC COMPOUND STIMULATING LIPID AND CARBOHYDRATE METABOLISMS AND AN ANTIOXIDANT AGENT FOR TREATING OBESITY | Les Laboratoires Servier (FR) | 2005-08-10 | — | — | EP | disclosed |
| WO-2004032968-A1 | ASSOCIATION BETWEEN A HETEROCYCLIC COMPOUND STIMULATING LIPID AND CARBOHYDRATE METABOLISMS AND AN ANTIOXIDANT AGENT FOR TREATING OBESITY | LES LABORATOIRES SERVIER (FR) | 2004-04-22 | — | — | WO | disclosed |
| EP-1252150-B1 | HETEROCYCLIC DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2003-06-04 | — | — | EP | disclosed |
| EP-1252150-A1 | NOVEL HETEROCYCLIC DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Les Laboratoires Servier (FR) | 2002-10-30 | — | — | EP | disclosed |
| WO-2001057002-A1 | NOVEL HETEROCYCLIC DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2001-08-09 | — | — | WO | disclosed |