Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.40 |
| ▸ | PPARD | Q03181 | 5/20 | 0.40 |
| ▸ | KDM1A | O60341 | 5/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6452169 | 1.00 | PRMT5 (0.44) | PRMT5ERN1FFAR1PPARDKDM1A | |
| SCHEMBL6452584 | 0.92 | PRMT5 (0.41) | PRMT5ERN1FFAR1PPARDKDM1A | |
| SCHEMBL6452573 | 0.92 | PRMT5 (0.41) | PRMT5ERN1FFAR1PPARDKDM1A | |
| SCHEMBL6455426 | 0.91 | PRMT5 (0.40) | PRMT5ERN1FFAR1PPARDKDM1A | |
| SCHEMBL6454639 | 0.91 | PRMT5 (0.42) | PRMT5ERN1FFAR1PPARDKDM1A | |
| SCHEMBL6455428 | 0.91 | PRMT5 (0.40) | PRMT5ERN1FFAR1PPARDKDM1A | |
| SCHEMBL6454634 | 0.91 | PRMT5 (0.42) | PRMT5ERN1FFAR1PPARDKDM1A | |
| SCHEMBL6461327 | 0.90 | PRMT5 (0.47) | PRMT5ERN1FFAR1PPARDKDM1A | |
| SCHEMBL6461332 | 0.90 | PRMT5 (0.47) | PRMT5ERN1FFAR1PPARDKDM1A | |
| SCHEMBL6456124 | 0.90 | PRMT5 (0.39) | PRMT5ERN1FFAR1PPARDKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |