Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6452207 | 1.00 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL7538026 | 1.00 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL8202426 | 0.93 | EDNRA (0.87) | EDNRAEDNRB | |
| SCHEMBL8202186 | 0.92 | EDNRB (0.86) | EDNRAEDNRB | |
| SCHEMBL7533846 | 0.91 | EDNRA (0.83) | EDNRAEDNRB | |
| SCHEMBL7942493 | 0.90 | EDNRA (0.81) | EDNRAEDNRB | |
| SCHEMBL7561291 | 0.89 | EDNRB (1.00) | EDNRAEDNRB | |
| SCHEMBL7561279 | 0.89 | EDNRB (1.00) | EDNRAEDNRB | |
| SCHEMBL8209842 | 0.89 | EDNRB (1.00) | EDNRAEDNRB | |
| SCHEMBL7561284 | 0.89 | EDNRB (1.00) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517708-A1 | COMBINATION TREATMENT FOR DEPRESSION AND ANXIETY BY NK1 AND NK3 ANTAGONISTS | Pfizer Products Inc. (US) | 2005-03-30 | — | — | EP | claimed |
| WO-2004000355-A1 | COMBINATION TREATMENT FOR DEPRESSION AND ANXIETY BY NK1 AND NK3 ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2003-12-31 | — | — | WO | claimed |