Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 12/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.30 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6452821 | 1.00 | SLC6A4 (0.56) | SLC6A4SLC6A2SLC6A3DRD2CYP1A2 | |
| SCHEMBL6459576 | 0.93 | SLC6A4 (0.54) | SLC6A4SLC6A2SLC6A3DRD2CYP1A2 | |
| SCHEMBL6459583 | 0.93 | SLC6A4 (0.54) | SLC6A4SLC6A2SLC6A3DRD2CYP1A2 | |
| SCHEMBL6456952 | 0.90 | SLC6A4 (0.51) | SLC6A4SLC6A2SLC6A3DRD2OPRL1 | |
| SCHEMBL6456955 | 0.90 | SLC6A4 (0.51) | SLC6A4SLC6A2SLC6A3DRD2OPRL1 | |
| SCHEMBL6451708 | 0.86 | SLC6A4 (0.49) | SLC6A4SLC6A2SLC6A3DRD2OPRL1 | |
| SCHEMBL6451703 | 0.86 | SLC6A4 (0.49) | SLC6A4SLC6A2SLC6A3DRD2OPRL1 | |
| SCHEMBL6452518 | 0.85 | SLC6A4 (0.53) | SLC6A4SLC6A2SLC6A3DRD2CYP1A2 | |
| SCHEMBL6452511 | 0.85 | SLC6A4 (0.53) | SLC6A4SLC6A2SLC6A3DRD2CYP1A2 | |
| SCHEMBL6458154 | 0.84 | SLC6A4 (0.47) | SLC6A4SLC6A2SLC6A3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |