Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 17/20 | 0.61 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.55 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.55 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4956147 | 0.89 | DPP4 (0.55) | DPP4DPP8DPP9DPP7OPRM1 | |
| SCHEMBL14282786 | 0.89 | DPP4 (0.55) | DPP4DPP8DPP9DPP7OPRM1 | |
| SCHEMBL4957948 | 0.88 | DPP4 (0.78) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL8290132 | 0.78 | DPP4 (0.51) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL4958143 | 0.78 | DPP4 (0.76) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL14282770 | 0.76 | DPP4 (0.68) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL4957611 | 0.76 | DPP4 (0.68) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL23752266 | 0.76 | DPP4 (1.00) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL8288995 | 0.76 | DPP4 (1.00) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL14421639 | 0.76 | DPP4 (0.67) | DPP4DPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1541143-A1 | DPP-IV INHIBITORS | Graffinity Pharmaceuticals Aktiengesellschaft (DE) | 2005-06-15 | — | — | EP | disclosed |