SCHEMBL6453471

SCHEMBL6453471

CCCCCCC1CC[C@@H]2C[C@H](c3ccc(-c4cc(F)c(OC(F)(F)F)c(F)c4)c(F)c3)CC[C@@H]2C1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
FASN P49327 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6453478 1.00 GAA (0.32) GAAMAPTFASN
SCHEMBL6452726 1.00 GAA (0.32) GAAMAPTFASN
SCHEMBL6452731 1.00 GAA (0.32) GAAMAPTFASN
SCHEMBL6458487 0.99 FASN (0.31) GAAMAPTFASN
SCHEMBL6458493 0.99 FASN (0.31) GAAMAPTFASN
SCHEMBL6456934 0.96 FASN (0.31) FASN
SCHEMBL6456937 0.96 FASN (0.31) FASN
SCHEMBL6460071 0.92 CYP2C9 (0.32) MAPTFASN
SCHEMBL6460074 0.92 CYP2C9 (0.32) MAPTFASN
SCHEMBL6459082 0.92 FASN (0.31) GAAMAPTFASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6913797-B1 Decahydronaphthalene derivative DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-07-05 US disclosed
EP-1108700-A1 DECAHYDRONAPHTHALENE DERIVATIVE DAINIPPON INK AND CHEMICALS, INC. (JP) 2001-06-20 EP disclosed