Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | FASN | P49327 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | USP7 | Q93009 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6453501 | 1.00 | APP (0.37) | APPFASNCYP2C19SLC6A2SLC6A4 | |
| SCHEMBL6453069 | 0.91 | FASN (0.38) | APPFASNCYP2C19SLC6A2SLC6A4 | |
| SCHEMBL6453071 | 0.91 | FASN (0.38) | APPFASNCYP2C19SLC6A2SLC6A4 | |
| SCHEMBL6461024 | 0.89 | FASN (0.37) | APPFASNCYP2C19SLC6A2SLC6A4 | |
| SCHEMBL6461021 | 0.89 | FASN (0.37) | APPFASNCYP2C19SLC6A2SLC6A4 | |
| SCHEMBL6452801 | 0.89 | FASN (0.37) | APPFASNCYP2C19SLC6A2SLC6A4 | |
| SCHEMBL6452792 | 0.89 | FASN (0.37) | APPFASNCYP2C19SLC6A2SLC6A4 | |
| SCHEMBL6455208 | 0.89 | FASN (0.38) | APPFASNCYP2C19SLC6A2SLC6A4 | |
| SCHEMBL6455206 | 0.89 | FASN (0.38) | APPFASNCYP2C19SLC6A2SLC6A4 | |
| SCHEMBL6454375 | 0.88 | FASN (0.34) | APPFASNCYP2C19CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |