Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | F7 | P08709 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 3/20 | 0.37 |
| ▸ | FLT3 | P36888 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | INSR | P06213 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6454465 | 1.00 | HTR2A (0.41) | HTR2ASLC5A7MAPK14F10GAA | |
| Hydrochloric Acid SCHEMBL5047768 | 0.99 | HTR2A (0.40) | HTR2ASLC5A7MAPK14F10GAA | |
| Hydrochloric Acid SCHEMBL5047761 | 0.99 | HTR2A (0.40) | HTR2ASLC5A7MAPK14F10GAA | |
| Hydrochloric Acid SCHEMBL5037625 | 0.92 | F10 (0.41) | HTR2ASLC5A7F10F2F7 | |
| Hydrochloric Acid SCHEMBL5037626 | 0.92 | F10 (0.41) | HTR2ASLC5A7F10F2F7 | |
| Hydrochloric Acid SCHEMBL5047483 | 0.91 | F10 (0.40) | HTR2ASLC5A7F10F2F7 | |
| Hydrochloric Acid SCHEMBL5047472 | 0.91 | F10 (0.40) | HTR2ASLC5A7F10F2F7 | |
| SCHEMBL6454314 | 0.88 | F10 (0.47) | HTR2ASLC5A7F10GAASMN1; SMN2 | |
| SCHEMBL6454327 | 0.88 | F10 (0.47) | HTR2ASLC5A7F10GAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5041200 | 0.88 | F10 (0.48) | HTR2ASLC5A7F10GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567498-A2 | MANDELIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004048335-A2 | MANDELIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-06-10 | — | — | WO | disclosed |