Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.70 |
| ▸ | RARG | P13631 | 7/20 | 0.70 |
| ▸ | RARA | P10276 | 6/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.70 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18678069 | 0.86 | RARB (0.65) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL24353029 | 0.83 | RARB (0.64) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL29462799 | 0.83 | RARB (0.64) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL29920484 | 0.83 | RARB (0.64) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL2915816 | 0.83 | RARB (0.64) | RARBRARGRARAMEN1KMT2A | |
| O-Demethylated Adapalene SCHEMBL174205 | 0.82 | RARG (1.00) | RARBRARGRARAMEN1KMT2A | |
| O-Demethylated Adapalene SCHEMBL29727107 | 0.82 | RARG (1.00) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL12890749 | 0.82 | RARB (0.62) | RARBRARGRARAMEN1KMT2A | |
| O-Demethylated Adapalene SCHEMBL29357288 | 0.82 | RARG (1.00) | RARBRARGRARAMEN1KMT2A | |
| O-Demethylated Adapalene SCHEMBL29357074 | 0.82 | RARG (1.00) | RARBRARGRARAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109589324-A | The therapeutic agent of angle disorder of conjunctiva | 国立大学法人山口大学 | 2019-04-09 | — | — | CN | claimed |
| CN-105188753-B | Therapeutic agent for keratoconjunctival disorder | 国立大学法人山口大学 | 2018-12-18 | — | — | CN | claimed |
| CN-103142460-B | Composition containing at least one naphthoic acid derivative, benzoyl peroxide and at least one film forming agent, their preparation method and its usage | 盖尔德马研究及发展公司 | 2016-08-31 | — | — | CN | disclosed |
| EP-1567172-A2 | FORMULATIONS USEFUL AGAINST HEPATITIS C VIRUS INFECTIONS | GPC Biotech AG (DE) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004050101-A3 | FORMULATIONS USEFUL AGAINST HEPATITIS C VIRUS INFECTIONS | AXXIMA PHARMACEUTICALS AG (DE) | 2004-09-10 | — | — | WO | disclosed |
| WO-2004050101-A2 | FORMULATIONS USEFUL AGAINST HEPATITIS C VIRUS INFECTIONS | GPC BIOTECH AG (DE) | 2004-06-17 | — | — | WO | disclosed |
| EP-0850067-A4 | METHOD FOR TREATING CANCERS USING 6- 3- 1-ADAMANTYL]-4-HYDROXYPHENYL] | CIRD GALDERMA (FR) | 1999-12-15 | — | — | EP | disclosed |
| EP-0850067-A1 | METHOD FOR TREATING CANCERS USING 6- 3- 1-ADAMANTYL]-4-HYDROXYPHENYL] | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1998-07-01 | — | — | EP | disclosed |
| WO-1997003682-A1 | METHOD FOR TREATING CANCERS USING 6-[3-[1-ADAMANTYL]-4-HYDROXYPHENYL] | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. GALDERMA (FR) | 1997-02-06 | — | — | WO | disclosed |