Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6455066 | 1.00 | TSHR (0.41) | TSHRSLC6A4SLC6A3GCGREPHX2 | |
| SCHEMBL5686611 | 0.94 | TSHR (0.39) | TSHRSLC6A4SLC6A3GCGREPHX2 | |
| SCHEMBL5686617 | 0.94 | TSHR (0.39) | TSHRSLC6A4SLC6A3GCGREPHX2 | |
| SCHEMBL8447740 | 0.93 | TSHR (0.43) | TSHRSLC6A4SLC6A3GCGRDRD2 | |
| SCHEMBL4803252 | 0.93 | TSHR (0.43) | TSHRSLC6A4SLC6A3GCGRDRD2 | |
| SCHEMBL4803267 | 0.93 | TSHR (0.43) | TSHRSLC6A4SLC6A3GCGRDRD2 | |
| SCHEMBL5344231 | 0.92 | TSHR (0.47) | TSHRSLC6A4SLC6A3GCGRDRD2 | |
| SCHEMBL5344223 | 0.92 | TSHR (0.47) | TSHRSLC6A4SLC6A3GCGRDRD2 | |
| SCHEMBL7731607 | 0.86 | GCGR (0.39) | TSHRSLC6A4SLC6A3GCGREPHX2 | |
| SCHEMBL7731604 | 0.86 | GCGR (0.39) | TSHRSLC6A4SLC6A3GCGREPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |