Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6456183 | 1.00 | SPHK1 (0.40) | SPHK1SPHK2CYP2C9NISCHP2RY14 | |
| SCHEMBL6458037 | 0.90 | CYP2C9 (0.41) | SPHK1SPHK2CYP2C9 | |
| SCHEMBL6458032 | 0.90 | CYP2C9 (0.41) | SPHK1SPHK2CYP2C9 | |
| SCHEMBL6453835 | 0.89 | SPHK1 (0.33) | SPHK1CYP2C9 | |
| SCHEMBL6453837 | 0.89 | SPHK1 (0.33) | SPHK1CYP2C9 | |
| SCHEMBL6459088 | 0.88 | SPHK1 (0.43) | SPHK1SPHK2CYP2C9 | |
| SCHEMBL6454169 | 0.88 | ACACB (0.44) | SPHK1SPHK2 | |
| SCHEMBL6454176 | 0.88 | ACACB (0.44) | SPHK1SPHK2 | |
| SCHEMBL6459098 | 0.88 | SPHK1 (0.43) | SPHK1SPHK2CYP2C9 | |
| SCHEMBL6454810 | 0.87 | SPHK1 (0.45) | SPHK1SPHK2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |