Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 7/20 | 0.34 |
| ▸ | KDM1A | O60341 | 4/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6456684 | 1.00 | PDE2A (0.34) | PDE2AKDM1AEPHX2HCRTR1HCRTR2 | |
| SCHEMBL6456687 | 1.00 | PDE2A (0.34) | PDE2AKDM1AEPHX2HCRTR1HCRTR2 | |
| SCHEMBL5684417 | 0.95 | PDE2A (0.33) | PDE2AKDM1AEPHX2 | |
| SCHEMBL5684415 | 0.95 | PDE2A (0.33) | PDE2AKDM1AEPHX2 | |
| SCHEMBL6456348 | 0.89 | KDM1A (0.42) | KDM1A | |
| SCHEMBL6456345 | 0.89 | KDM1A (0.42) | KDM1A | |
| SCHEMBL6456352 | 0.89 | KDM1A (0.42) | KDM1A | |
| SCHEMBL15581123 | 0.89 | PDE2A (0.33) | PDE2AKDM1AEPHX2 | |
| SCHEMBL5684174 | 0.87 | PDE2A (0.33) | PDE2AKDM1AEPHX2HCRTR1HCRTR2 | |
| SCHEMBL5684167 | 0.87 | PDE2A (0.33) | PDE2AKDM1AEPHX2HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |