SCHEMBL6456700

SCHEMBL6456700

O=CC1CCC(C2CC[C@H]3CC(c4cc(F)cc(F)c4)CC[C@@H]3C2)CC1

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.30
SLC6A4 P31645 2/20 0.30
SLC6A3 Q01959 2/20 0.30
NPY5R Q15761 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6456704 1.00 SLC6A2 (0.30) SLC6A2SLC6A4SLC6A3NPY5R
SCHEMBL6458166 0.92 NPY5R (0.30) NPY5R
SCHEMBL6458163 0.92 NPY5R (0.30) NPY5R
SCHEMBL7851738 0.85 HCRTR2 (0.36) NPY5R
SCHEMBL16210861 0.85 HCRTR2 (0.36) NPY5R
SCHEMBL6456555 0.84 SLC6A2 (0.30) SLC6A2SLC6A4SLC6A3
SCHEMBL6456552 0.84 SLC6A2 (0.30) SLC6A2SLC6A4SLC6A3
SCHEMBL6460965 0.79 ESR2 (0.32) SLC6A2SLC6A4SLC6A3NPY5R
SCHEMBL6460962 0.79 ESR2 (0.32) SLC6A2SLC6A4SLC6A3NPY5R
SCHEMBL6459992 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6913797-B1 Decahydronaphthalene derivative DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-07-05 US disclosed
EP-1108700-A1 DECAHYDRONAPHTHALENE DERIVATIVE DAINIPPON INK AND CHEMICALS, INC. (JP) 2001-06-20 EP disclosed