Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 14/20 | 0.39 |
| ▸ | HTR2B | P41595 | 8/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 8/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | HRH2 | P25021 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6456804 | 1.00 | HTR2C (0.39) | HTR2CHTR2BPDE4APDE4BPDE4C | |
| SCHEMBL6462533 | 0.90 | KDM1A (0.36) | HTR2CHTR2BPDE4APDE4BPDE4C | |
| SCHEMBL6460540 | 0.90 | HTR2C (0.38) | HTR2CHTR2BPDE4APDE4BPDE4C | |
| SCHEMBL6460547 | 0.90 | HTR2C (0.38) | HTR2CHTR2BPDE4APDE4BPDE4C | |
| SCHEMBL6462526 | 0.90 | KDM1A (0.36) | HTR2CHTR2BPDE4APDE4BPDE4C | |
| SCHEMBL6460542 | 0.90 | HTR2C (0.38) | HTR2CHTR2BPDE4APDE4BPDE4C | |
| SCHEMBL6462531 | 0.90 | KDM1A (0.36) | HTR2CHTR2BPDE4APDE4BPDE4C | |
| SCHEMBL6456108 | 0.88 | KDM1A (0.37) | HTR2CHTR2BPDE4APDE4BPDE4C | |
| SCHEMBL6456104 | 0.88 | KDM1A (0.37) | HTR2CHTR2BPDE4APDE4BPDE4C | |
| SCHEMBL6456100 | 0.88 | KDM1A (0.37) | HTR2CHTR2BPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |