Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.37 |
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.30 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.30 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.30 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6457324 | 1.00 | CYP11B1 (0.37) | CYP11B1CYP11B2FASNCYP2C9ALDH1A1 | |
| SCHEMBL6464170 | 0.94 | CYP11B1 (0.36) | CYP11B1CYP11B2FASN | |
| SCHEMBL6464165 | 0.94 | CYP11B1 (0.36) | CYP11B1CYP11B2FASN | |
| SCHEMBL6458156 | 0.93 | CYP11B1 (0.35) | CYP11B1CYP11B2FASN | |
| SCHEMBL6458152 | 0.93 | CYP11B1 (0.35) | CYP11B1CYP11B2FASN | |
| SCHEMBL6464023 | 0.92 | CYP11B1 (0.35) | CYP11B1CYP11B2FASNMAPT | |
| SCHEMBL6461279 | 0.92 | CYP11B1 (0.35) | CYP11B1CYP11B2FASNMAPT | |
| SCHEMBL6464025 | 0.92 | CYP11B1 (0.35) | CYP11B1CYP11B2FASNMAPT | |
| SCHEMBL6461276 | 0.92 | CYP11B1 (0.35) | CYP11B1CYP11B2FASNMAPT | |
| SCHEMBL6453452 | 0.91 | CYP11B1 (0.36) | CYP11B1CYP11B2FASNCYP2C9PSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |