Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 6/20 | 0.34 |
| ▸ | DPP4 | P27487 | 4/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6457632 | 1.00 | SLC6A4 (0.34) | SLC6A4SLC6A2SLC6A3LRRK2DPP4 | |
| SCHEMBL6456885 | 0.85 | SLC6A4 (0.34) | SLC6A4SLC6A2SLC6A3LRRK2DPP4 | |
| SCHEMBL6456881 | 0.85 | SLC6A4 (0.34) | SLC6A4SLC6A2SLC6A3LRRK2DPP4 | |
| SCHEMBL6459396 | 0.84 | SLC6A4 (0.39) | SLC6A4SLC6A2SLC6A3LRRK2HTR1A | |
| SCHEMBL6459394 | 0.84 | SLC6A4 (0.39) | SLC6A4SLC6A2SLC6A3LRRK2HTR1A | |
| SCHEMBL6457373 | 0.84 | SLC6A4 (0.34) | SLC6A4SLC6A2SLC6A3LRRK2DPP4 | |
| SCHEMBL6457377 | 0.84 | SLC6A4 (0.34) | SLC6A4SLC6A2SLC6A3LRRK2DPP4 | |
| SCHEMBL6453017 | 0.83 | SLC6A2 (0.46) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6453019 | 0.83 | SLC6A2 (0.46) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6464965 | 0.82 | KDM1A (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |