⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6353257 | 0.74 | — | — | |
| SCHEMBL7913897 | 0.70 | — | — | |
| Trimethylammonium SCHEMBL20854543 | 0.63 | — | — | |
| SCHEMBL31435651 | 0.62 | CA1 (0.32) | — | |
| SCHEMBL26223481 | 0.59 | — | — | |
| SCHEMBL18602707 | 0.59 | — | — | |
| SCHEMBL25137255 | 0.58 | — | — | |
| SCHEMBL18633453 | 0.56 | — | — | |
| SCHEMBL24616659 | 0.56 | — | — | |
| SCHEMBL18949237 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1042 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118026919-A | Preparation method of 3, 3-difluoro-4-piperidone hydrochloride | 南京法恩化学有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-117327322-A | Preparation method of modified polyether-ether-ketone with antibacterial property on surface | 吉林大学 | 2024-01-02 | — | — | CN | claimed |
| CN-117024324-A | Preparation method of tafluprost enantiomer | 南京华威医药科技集团有限公司 | 2023-11-10 | — | — | CN | claimed |
| CN-116837364-A | Preparation method and application of metallic lithium surface protection layer | 厦门大学 | 2023-10-03 | — | — | CN | claimed |
| CN-112457362-B | Halogenated tetracyclic triterpene derivative and preparation and application thereof | 上海青东生物科技有限公司 | 2023-09-19 | — | — | CN | claimed |
| EP-4043447-A1 | HALOGENATED TETRACYCLIC TRITERPENE DERIVATIVE, PREPARATION AND APPLICATION THEREOF | Shanghai King-X Biotech Co., Ltd. (CN) | 2022-08-17 | — | — | EP | claimed |
| US-20220177511-A1 | SERIES OF HALOGENATED TETRACYCLIC TRITERPENE DERIVATIVES AND THEIR PREPARATION AND APPLICATION | Shanghai Qingdong Biotechnology Co., Ltd. (CN) | 2022-06-09 | — | — | US | claimed |
| WO-2021043194-A1 | HALOGENATED TETRACYCLIC TRITERPENE DERIVATIVE, PREPARATION AND APPLICATION THEREOF | 上海青玄生物科技有限公司 | 2021-03-11 | — | — | WO | claimed |
| CN-112457362-A | Halogenated tetracyclic triterpene derivative and preparation and application thereof | 上海青玄生物科技有限公司 | 2021-03-09 | — | — | CN | claimed |
| WO-2018134343-A1 | SYNTHESIS OF PHOSPHORAMIDATES | SANDOZ AG (CH) | 2018-07-26 | — | — | WO | claimed |
| CN-101233098-A | Process for the preparation of geminal ((difluorocycloalkyl) methyl) amines | ASTRAZENECA AB (SE) | 2008-07-30 | — | — | CN | claimed |
| US-20080167488-A1 | Process for the Preparation of Geminal ((Difluorocycloalkyl)Methyl) Amines | ASTRAZENECA AB (SE) | 2008-07-10 | — | — | US | claimed |
| EP-1912930-A1 | PROCESS FOR THE PREPARATION OF GEMINAL ((DIFLUOROCYCLOALKYL)METHYL) AMINES. | AstraZeneca AB (SE) | 2008-04-23 | — | — | EP | claimed |
| WO-2007132314-A2 | SUBSTITUTED PIPERIDINO PHENYLOXAZOLIDINONES | WOCKHARDT LTD (IN) | 2007-11-22 | — | — | WO | claimed |
| WO-2007013848-A1 | PROCESS FOR THE PREPARATION OF GEMINAL ((DIFLUOROCYCLOALKYL)METHYL) AMINES. | ASTRAZENECA AB (SE) | 2007-02-01 | — | — | WO | claimed |
| US-6344558-B1 | ANALGESICS | GRUENTHAL GMBH (DE) | 2002-02-05 | — | — | US | claimed |
| US-20020010178-A1 | 1-phenyl-3-dimethylaminopropane compounds with a pharmacological effect | GRUENENTHAL GMBH | 2002-01-24 | — | — | US | claimed |
| EP-0753506-B1 | 6-Dimethylaminomethyl-1-phenyl-cyclo-hexane compounds as pharmaceutical agents | GRUENENTHAL GMBH (DE) | 1999-08-18 | — | — | EP | claimed |
| EP-0693475-B1 | 1-Phenyl-3-dimethylamino-propane derivatives having pharmacological activity | GRUENENTHAL GMBH (DE) | 1998-02-11 | — | — | EP | claimed |
| US-4284764-A | Process for the preparation of 5-fluoro-5-deoxy and 5-epi-fluoro-5-deoxy-4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitols and novel 5-fluoro-5-deoxy and 5-epi-fluoro-5-deoxy derivatives produced thereby | SCHERING CORPORATION (US) | 1981-08-18 | — | — | US | claimed |