Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PLAT | P00750 | 1/20 | 0.47 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.41 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | DHCR24 | Q15392 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19924308 | 0.83 | PLG (0.50) | LMNAPLGPLATTPSAB1TPSD1 | |
| SCHEMBL12476221 | 0.82 | CHRM2 (0.42) | LMNACYP2D6CHRM2CHRM1CHRM4 | |
| SCHEMBL177205 | 0.82 | — | — | |
| SCHEMBL13888364 | 0.81 | PLG (0.41) | LMNAPLGPLATTPSAB1TPSD1 | |
| SCHEMBL28726529 | 0.81 | PLG (0.48) | LMNAPLGPLATTPSAB1TPSD1 | |
| SCHEMBL28563130 | 0.81 | PLG (0.48) | LMNAPLGPLATTPSAB1TPSD1 | |
| SCHEMBL9506281 | 0.81 | PLG (0.54) | LMNAPLGPLATTPSAB1TPSD1 | |
| SCHEMBL15712634 | 0.81 | CYP19A1 (0.49) | LMNACYP2D6CYP19A1CHRM2CHRM1 | |
| SCHEMBL28563135 | 0.81 | PLG (0.48) | LMNAPLGPLATTPSAB1TPSD1 | |
| SCHEMBL9505982 | 0.81 | PLG (0.54) | LMNAPLGPLATTPSAB1TPSD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3700595-B1 | KITS FOR ANCHORING IMPLANTABLE MEDICAL DEVICES | MEDTRONIC INC (US) | 2024-06-19 | — | — | EP | disclosed |
| CN-114181077-B | Method for synthesizing tranexamic acid | 风火轮(上海)生物科技有限公司 | 2024-02-27 | — | — | CN | disclosed |
| US-11191878-B2 | Kits for local delivery of water soluble agents and methods of use | MEDTRONIC, INC. (US) | 2021-12-07 | — | — | US | disclosed |
| US-20200345901-A1 | KITS FOR LOCAL DELIVERY OF WATER SOLUBLE AGENTS AND METHODS OF USE | MEDTRONIC, INC. (US) | 2020-11-05 | — | — | US | disclosed |
| EP-3700595-A1 | KITS FOR ANCHORING IMPLANTABLE MEDICAL DEVICES | Medtronic, Inc. (US) | 2020-09-02 | — | — | EP | disclosed |
| US-10736998-B2 | Kits for local delivery of water soluble agents and methods of use | MEDTRONIC, INC. (US) | 2020-08-11 | — | — | US | disclosed |
| US-20190262510-A1 | KITS FOR LOCAL DELIVERY OF WATER SOLUBLE AGENTS AND METHODS OF USE | MEDTRONIC, INC. (US) | 2019-08-29 | — | — | US | disclosed |
| US-10314951-B2 | Kits for local delivery of water soluble agents and methods of use | MEDTRONIC, INC. (US) | 2019-06-11 | — | — | US | disclosed |
| US-20190125938-A1 | KITS FOR LOCAL DELIVERY OF WATER SOLUBLE AGENTS AND METHODS OF USE | TYRX, INC. (US) | 2019-05-02 | — | — | US | disclosed |
| US-10034969-B1 | Kits for local delivery of water soluble agents and methods of use | TYRX, INC. (US) | 2018-07-31 | — | — | US | disclosed |
| US-9987400-B1 | Kits for local delivery of water soluble agents and methods of use | TYRX, INC. (US) | 2018-06-05 | — | — | US | disclosed |
| US-9919080-B1 | Kits for local delivery of water soluble agents and methods of use | TYRX, INC. (US) | 2018-03-20 | — | — | US | disclosed |
| CN-105026407-B | Beta-lactamase inhibitors | 维纳拓尔斯制药公司 | 2017-09-08 | — | — | CN | disclosed |
| EP-1534700-A1 | NOVEL THIOPHENE DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004018448-A1 | NOVEL THIOPHENE DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | WARNER-LAMBERT COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |