SCHEMBL6457937

SCHEMBL6457937

CNC(=O)C(=NOC)c1ccccc1COc1ccc(Cl)cc1C

nearest known ligand 0.60

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 6/20 0.52
ANO1 Q5XXA6 3/20 0.48
MRGPRX4 Q96LA9 6/20 0.48
ANO2 Q9NQ90 1/20 0.47
MAPT P10636 1/20 0.44
PTGDR2 Q9Y5Y4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6457931 1.00 HIF1A (0.52) HIF1AANO1MRGPRX4ANO2MAPT
SCHEMBL8369903 1.00 HIF1A (0.52) HIF1AANO1MRGPRX4ANO2MAPT
SCHEMBL8395204 0.91 MRGPRX4 (0.47) HIF1AANO1MRGPRX4ANO2MAPT
SCHEMBL8395210 0.91 MRGPRX4 (0.47) HIF1AANO1MRGPRX4ANO2MAPT
SCHEMBL6452972 0.91 MRGPRX4 (0.61) HIF1AMRGPRX4
SCHEMBL8371588 0.91 MRGPRX4 (0.61) HIF1AMRGPRX4
SCHEMBL6452979 0.91 MRGPRX4 (0.61) HIF1AMRGPRX4
SCHEMBL8617226 0.90 HIF1A (0.53) HIF1AANO1MRGPRX4ANO2MAPT
SCHEMBL8617228 0.90 HIF1A (0.53) HIF1AANO1MRGPRX4ANO2MAPT
SCHEMBL8400204 0.90 HIF1A (0.51) HIF1AANO1MRGPRX4ANO2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030055096-A1 Fungicidal composition OGURI YUKIO (JP) 2003-03-20 US claimed
EP-0741970-A1 BACTERICIDAL COMPOSITION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-11-13 EP claimed
JP-7285811-A None JP disclosed
JP-7187918-A None JP disclosed
JP-7304606-A None JP disclosed
JP-8026920-A None JP disclosed
JP-7324008-A None JP disclosed
JP-7187917-A None JP disclosed
US-6838482-B2 Fungicidal composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-01-04 US disclosed
US-20030055096-A1 Fungicidal composition OGURI YUKIO (JP) 2003-03-20 US disclosed
EP-0644183-B1 Process of producing N-alkylacetamides SHIONOGI & CO (JP) 1999-06-02 EP disclosed
JP-H0826920-A FUNGICIDE COMPOSITION SUMITOMO CHEM CO LTD 1996-01-30 JP disclosed
JP-H07324008-A FUNGICIDE COMPOSITION SUMITOMO CHEM CO LTD 1995-12-12 JP disclosed
JP-H07304606-A GERMICIDAL COMPOSITION SUMITOMO CHEM CO LTD 1995-11-21 JP disclosed
JP-H07285811-A GERMICIDAL COMPOSITION SUMITOMO CHEM CO LTD 1995-10-31 JP disclosed
JP-H07187917-A FUNGICIDE COMPOSITION SUMITOMO CHEM CO LTD 1995-07-25 JP disclosed
JP-H07187918-A FUNGICIDE COMPOSITION SUMITOMO CHEM CO LTD 1995-07-25 JP disclosed
EP-0658541-A1 PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE SHIONOGI & CO., LTD. (JP) 1995-06-21 EP disclosed
EP-0644183-A2 Process of producing N-alkylacetamides SHIONOGI & CO., LTD. (JP) 1995-03-22 EP disclosed
EP-0617011-A2 Process for producing alkoxyiminoacetamide compounds SHIONOGI & CO., LTD. (JP) 1994-09-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030055096-A1 Fungicidal composition CBR1, CBR3, CYP1B1 HIF1A 2640/4885ANO1 1831/4885MRGPRX4 1359/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.