Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | MAT2A | P31153 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CCR6 | P51684 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6457985 | 1.00 | DRD1 (0.38) | DRD1IDO1MAT2ANPSR1KMT2A | |
| SCHEMBL6451340 | 0.86 | IDO1 (0.34) | DRD1IDO1MAT2AKMT2AALDH1A1 | |
| SCHEMBL6451344 | 0.86 | IDO1 (0.34) | DRD1IDO1MAT2AKMT2AALDH1A1 | |
| SCHEMBL6455657 | 0.84 | IDO1 (0.35) | DRD1IDO1MAT2AALDH1A1LMNA | |
| SCHEMBL6455665 | 0.84 | IDO1 (0.35) | DRD1IDO1MAT2AALDH1A1LMNA | |
| SCHEMBL6455658 | 0.84 | IDO1 (0.35) | DRD1IDO1MAT2AALDH1A1LMNA | |
| SCHEMBL6451194 | 0.82 | KDM1A (0.39) | KMT2AALDH1A1RAB9AMEN1 | |
| SCHEMBL6451193 | 0.82 | KDM1A (0.39) | KMT2AALDH1A1RAB9AMEN1 | |
| SCHEMBL6455186 | 0.81 | KDM1A (0.34) | — | |
| SCHEMBL6455188 | 0.81 | KDM1A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |