Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 11/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6458055 | 1.00 | SLC6A4 (0.40) | SLC6A4SLC6A2SLC6A3IDO1ABL1 | |
| SCHEMBL6456364 | 0.91 | SLC6A4 (0.37) | SLC6A4SLC6A2SLC6A3IDO1ABL1 | |
| SCHEMBL6456369 | 0.91 | SLC6A4 (0.37) | SLC6A4SLC6A2SLC6A3IDO1ABL1 | |
| SCHEMBL6453657 | 0.89 | SLC6A4 (0.35) | SLC6A4SLC6A2SLC6A3IDO1ABL1 | |
| SCHEMBL6453652 | 0.89 | SLC6A4 (0.35) | SLC6A4SLC6A2SLC6A3IDO1ABL1 | |
| SCHEMBL6452428 | 0.88 | SLC6A4 (0.35) | SLC6A4SLC6A2SLC6A3IDO1ABL1 | |
| SCHEMBL6452437 | 0.88 | SLC6A4 (0.35) | SLC6A4SLC6A2SLC6A3IDO1ABL1 | |
| SCHEMBL6459531 | 0.87 | SLC6A4 (0.34) | SLC6A4SLC6A2SLC6A3IDO1ABL1 | |
| SCHEMBL6459638 | 0.87 | SLC6A4 (0.34) | SLC6A4SLC6A2SLC6A3IDO1ABL1 | |
| SCHEMBL6459534 | 0.87 | SLC6A4 (0.34) | SLC6A4SLC6A2SLC6A3IDO1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |