Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | WDR5 | P61964 | 2/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.31 |
| ▸ | LIPE | Q05469 | 1/20 | 0.30 |
| ▸ | GPR3 | P46089 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6458187 | 1.00 | SCN9A (0.37) | SCN9AFASNDRD2DRD3TRPV3 | |
| SCHEMBL6450921 | 0.92 | FASN (0.36) | SCN9AFASNDRD2DRD3TRPV3 | |
| SCHEMBL6450924 | 0.92 | FASN (0.36) | SCN9AFASNDRD2DRD3TRPV3 | |
| SCHEMBL6454522 | 0.91 | FASN (0.35) | SCN9AFASNDRD2DRD3TRPV3 | |
| SCHEMBL6454520 | 0.91 | FASN (0.35) | SCN9AFASNDRD2DRD3TRPV3 | |
| SCHEMBL6455062 | 0.90 | FASN (0.34) | SCN9AFASNDRD2DRD3TRPV3 | |
| SCHEMBL6455067 | 0.90 | FASN (0.34) | SCN9AFASNDRD2DRD3TRPV3 | |
| SCHEMBL6454251 | 0.89 | FASN (0.34) | SCN9AFASNDRD2DRD3TRPV3 | |
| SCHEMBL6452370 | 0.89 | FASN (0.34) | SCN9AFASNDRD2DRD3TRPV3 | |
| SCHEMBL6454256 | 0.89 | FASN (0.34) | SCN9AFASNDRD2DRD3TRPV3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |