Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TTK | P33981 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6458354 | 1.00 | KDM1A (0.40) | KDM1ASLC6A2SLC6A4SLC6A3CYP19A1 | |
| SCHEMBL6452666 | 0.88 | SLC6A4 (0.39) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6452670 | 0.88 | SLC6A4 (0.39) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6452713 | 0.87 | SLC6A2 (0.33) | KDM1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6457664 | 0.87 | SLC6A2 (0.33) | KDM1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6457666 | 0.87 | SLC6A2 (0.33) | KDM1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6452710 | 0.87 | SLC6A2 (0.33) | KDM1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6454180 | 0.85 | SLC6A2 (0.39) | KDM1ASLC6A2SLC6A4SLC6A3CYP19A1 | |
| SCHEMBL6454175 | 0.85 | SLC6A2 (0.39) | KDM1ASLC6A2SLC6A4SLC6A3CYP19A1 | |
| SCHEMBL6457944 | 0.83 | HTR2C (0.35) | SLC6A2SLC6A4SLC6A3PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |