Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | GCGR | P47871 | 1/20 | 0.30 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6454089 | 1.00 | FASN (0.34) | FASNGAAMAPTRARBCYP11B1 | |
| SCHEMBL6458629 | 1.00 | FASN (0.34) | FASNGAAMAPTRARBCYP11B1 | |
| SCHEMBL6454084 | 1.00 | FASN (0.34) | FASNGAAMAPTRARBCYP11B1 | |
| SCHEMBL6460167 | 0.99 | FASN (0.35) | FASNGAAMAPTRARBCYP11B1 | |
| SCHEMBL6460171 | 0.99 | FASN (0.35) | FASNGAAMAPTRARBCYP11B1 | |
| SCHEMBL6459811 | 0.96 | FASN (0.35) | FASNCYP11B1CYP11B2 | |
| SCHEMBL6459809 | 0.96 | FASN (0.35) | FASNCYP11B1CYP11B2 | |
| SCHEMBL6457917 | 0.91 | FASN (0.36) | FASNMAPTCYP11B1CYP11B2CYP3A4 | |
| SCHEMBL6457908 | 0.91 | FASN (0.36) | FASNMAPTCYP11B1CYP11B2CYP3A4 | |
| SCHEMBL6464023 | 0.91 | CYP11B1 (0.35) | FASNGAAMAPTRARBCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |