SCHEMBL645880

SCHEMBL645880

CCCCCCCCCCCCCCCCCC.N=C=O.N=C=O

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.57
THRB P10828 1/20 0.57
CES2 O00748 3/20 0.43
CES1 P23141 3/20 0.43
EPHX2 P34913 1/20 0.43
DNM1 Q05193 5/20 0.42
ALDH1A1 P00352 2/20 0.42
LMNA P02545 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
HSD17B10 Q99714 1/20 0.42
SLC22A1 O15245 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dodecane SCHEMBL4218486 1.00 TSHR (0.57) TSHRTHRBCES2CES1EPHX2
SCHEMBL25272132 1.00 TSHR (0.57) TSHRTHRBCES2CES1EPHX2
Pentadecane SCHEMBL25170626 1.00 TSHR (0.57) TSHRTHRBCES2CES1EPHX2
Tetradecane SCHEMBL25170575 1.00 TSHR (0.57) TSHRTHRBCES2CES1EPHX2
SCHEMBL25176379 1.00 TSHR (0.57) TSHRTHRBCES2CES1EPHX2
SCHEMBL25169788 1.00 TSHR (0.57) TSHRTHRBCES2CES1EPHX2
Tridecane SCHEMBL25167740 1.00 TSHR (0.57) TSHRTHRBCES2CES1EPHX2
Hexadecane SCHEMBL25176598 1.00 TSHR (0.57) TSHRTHRBCES2CES1EPHX2
Tetradecane SCHEMBL8743025 1.00 TSHR (0.57) TSHRTHRBCES2CES1EPHX2
Tridecane SCHEMBL362513 1.00 TSHR (0.57) TSHRTHRBCES2CES1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 414 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117736786-A Polyurea lubricating grease composition and preparation and application thereof 亚培烯科技(上海)有限公司 2024-03-22 CN claimed
CN-108863966-B Process for preparing trimers and/or oligomers of diisocyanates 赢创运营有限公司 2023-12-08 CN claimed
EP-3762438-A1 BIOCIDAL COATING MATERIAL AND ASSOCIATED PRODUCTION PROCESS El Kudsi, Karim (DE) 2021-01-13 EP claimed
US-10793664-B2 Process for preparing trimers and/or oligomers of diisocyanates EVONIK OPERATIONS GMBH (DE) 2020-10-06 US claimed
EP-3401344-B1 METHOD FOR THE PREPARATION OF TRIMERS AND/OR OLIGOMERS OF DIISOCYANATES EVONIK OPERATIONS GMBH (DE) 2020-04-08 EP claimed
WO-2019170653-A1 BIOCIDAL COATING MATERIAL AND ASSOCIATED PRODUCTION PROCESS EL KUDSI KARIM (DE) 2019-09-12 WO claimed
CN-108863966-A The method for preparing the trimer and/or oligomer of diisocyanate 赢创德固赛有限公司 2018-11-23 CN claimed
US-20180327538-A1 PROCESS FOR PREPARING TRIMERS AND/OR OLIGOMERS OF DIISOCYANATES EVONIK OPERATIONS GMBH (DE) 2018-11-15 US claimed
US-7762894-B2 Constant velocity joint HONDA MOTOR CO., LTD. (JP) 2010-07-27 US claimed
US-20070298890-A1 Constant Velocity Joint HONDA MOTOR CO., LTD. (JP) 2007-12-27 US claimed
EP-1820988-A1 CONSTANT VELOCITY JOINT HONDA MOTOR CO., Ltd. (JP) 2007-08-22 EP claimed
EP-1274757-A2 LOW TEMPERATURE CURE MDI PREPOLYMERS HUNTSMAN INTERNATIONAL LLC (US) 2003-01-15 EP claimed
US-20020010304-A1 Low temperature cure MDI prepolymers DEUTSCHE BANK TRUST COMPANY AMERICAS, AS AGENT 2002-01-24 US claimed
US-6319880-B1 EFFICIENT, USED TO LUBRICATE THE PORTIONS OF SLIDING TYPE CONSTANT VELOCITY JOINTS OF MOTORCARS, DURABILITY KYODO YUSHI CO., LTD. (JP) 2001-11-20 US claimed
WO-2001070839-A2 LOW TEMPERATURE CURE MDI PREPOLYMERS HUNTSMAN INTERNATIONAL LLC (US) 2001-09-27 WO claimed
US-5783658-A Phase change ink formulation using a urethane isocyanate-derived resin and a urethane isocyanate-derived wax TEKTRONIX, INC. (US) 1998-07-21 US claimed
EP-0816447-A1 Phase change ink formulation using a urethane isocyanate-derived resin and a urethane isocyanate-derived wax TEKTRONIX, INC. (US) 1998-01-07 EP claimed
US-3972846-A Curable urethane resin composition comprising a mixture of polyisocyanate, active hydrogen compound and diketo compound SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-08-03 US claimed
EP-4407014-B1 USE OF A LUBRICANT COMPOSITION AND ROLLING BEARING NTN TOYO BEARING CO LTD (JP) 2026-05-20 EP disclosed
US-3972846-A Curable urethane resin composition comprising a mixture of polyisocyanate, active hydrogen compound and diketo compound SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-08-03 US disclosed