Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 15/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 15/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 13/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6458861 | 1.00 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3HTR3AKCNH2 | |
| SCHEMBL6452786 | 0.90 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3HTR3AKCNH2 | |
| SCHEMBL6452797 | 0.90 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3HTR3AKCNH2 | |
| SCHEMBL6462506 | 0.88 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3HTR3AKCNH2 | |
| SCHEMBL6462502 | 0.88 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3HTR3AKCNH2 | |
| SCHEMBL6459908 | 0.87 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3HTR3AKCNH2 | |
| SCHEMBL6459910 | 0.87 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3HTR3AKCNH2 | |
| SCHEMBL14228604 | 0.87 | GRIA1 (0.39) | KCNH2DRD2DRD3 | |
| SCHEMBL6459013 | 0.86 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3HTR3AKCNH2 | |
| SCHEMBL6459017 | 0.86 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3HTR3AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |