SCHEMBL6458988

SCHEMBL6458988

C=CCCC1CCC2CC(C3CCC(CCC)CC3)CCC2C1

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TLR4 O00206 2/20 0.37
TSHR P16473 2/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6458983 1.00 TLR4 (0.37) TLR4TSHRALDH1A1
SCHEMBL8045333 0.91 TSHR (0.39) TLR4TSHRALDH1A1
SCHEMBL7909232 0.86 TSHR (0.37) TLR4TSHRALDH1A1
SCHEMBL7909218 0.86 TSHR (0.37) TLR4TSHRALDH1A1
SCHEMBL7909226 0.86 TSHR (0.37) TLR4TSHRALDH1A1
SCHEMBL6454890 0.85
SCHEMBL7523435 0.85 TSHR (0.43) TSHRALDH1A1
SCHEMBL6454895 0.85
SCHEMBL11026319 0.85 TLR4 (0.44) TLR4ALDH1A1
SCHEMBL9979173 0.82 TLR4 (0.35) TLR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6913797-B1 Decahydronaphthalene derivative DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-07-05 US disclosed