SCHEMBL6459049

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6459056	1.00	MCHR1 (0.43)	MCHR1EPHX2ACHEBACE1L3MBTL1
	SCHEMBL6869412	0.89	EPHX2 (0.55)	MCHR1EPHX2ACHEBACE1L3MBTL1
	SCHEMBL6869407	0.89	EPHX2 (0.55)	MCHR1EPHX2ACHEBACE1L3MBTL1
	SCHEMBL6455517	0.89	CYP3A4 (0.47)	MCHR1CNR1NPC1KCNH2AURKB
	SCHEMBL6455512	0.89	CYP3A4 (0.47)	MCHR1CNR1NPC1KCNH2AURKB
	SCHEMBL6456315	0.89	MCHR1 (0.50)	MCHR1ACHEBACE1NPC1RAB9A
	SCHEMBL6868664	0.89	MCHR1 (0.50)	MCHR1ACHEBACE1NPC1RAB9A
	SCHEMBL6456307	0.89	MCHR1 (0.50)	MCHR1ACHEBACE1NPC1RAB9A
	SCHEMBL6868658	0.89	MCHR1 (0.50)	MCHR1ACHEBACE1NPC1RAB9A
	SCHEMBL6873825	0.89	MCHR1 (0.45)	MCHR1NPC1RAB9AAURKBADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.