Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 14/20 | 0.36 |
| ▸ | DRD2 | P14416 | 12/20 | 0.36 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6459249 | 1.00 | DRD3 (0.36) | DRD3DRD2CYP26A1CYP3A4CYP2C8 | |
| SCHEMBL6458310 | 0.90 | CYP3A4 (0.37) | DRD3DRD2CYP26A1CYP3A4CYP2C8 | |
| SCHEMBL6458305 | 0.90 | CYP3A4 (0.37) | DRD3DRD2CYP26A1CYP3A4CYP2C8 | |
| SCHEMBL6450769 | 0.87 | S1PR3 (0.43) | DRD3DRD2CYP3A4CYP2C8CYP2D6 | |
| SCHEMBL6450764 | 0.87 | S1PR3 (0.43) | DRD3DRD2CYP3A4CYP2C8CYP2D6 | |
| SCHEMBL6453661 | 0.86 | S1PR3 (0.47) | DRD3DRD2CYP3A4CYP2C8CYP2D6 | |
| SCHEMBL6453655 | 0.86 | S1PR3 (0.47) | DRD3DRD2CYP3A4CYP2C8CYP2D6 | |
| SCHEMBL6457300 | 0.85 | S1PR3 (0.48) | DRD3DRD2CYP3A4CYP2C8CYP2D6 | |
| SCHEMBL6454132 | 0.85 | S1PR3 (0.48) | DRD3DRD2CYP3A4CYP2C8CYP2D6 | |
| SCHEMBL6457294 | 0.85 | S1PR3 (0.48) | DRD3DRD2CYP3A4CYP2C8CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |